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| Asano,R.Y.; Browne,R.A.V.; Sales,M.M.; Arsa,G.; Moraes,J.F.V.N.; Coelho-Júnior,H.J.; Moraes,M.R.; Oliveira-Silva,I.; Atlas,S.E.; Lewis,J.E.; Simões,H.G.. |
| The aim of this study was to analyze the acute responses of bradykinin, insulin, and glycemia to exercise performed above and below lactate threshold (LT) in individuals with type 2 diabetes mellitus (T2D). Eleven participants with a diagnosis of T2D randomly underwent three experimental sessions 72 h apart: 1) 20 min of exercise performed at 120% of LT (120%LT), 2) 20 min of exercise performed at 80% of LT (80%LT), and 3) 20 min of control session. Blood glucose was analyzed before, during, and at 45 min post-exercise. Bradykinin and insulin were analyzed before and at 45 min post-exercise. Both exercise sessions elicited a parallel decrease in glucose level during exercise (P≤0.002), with a greater decrease being observed for 120%LT (P=0.005). Glucose... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Metabolic disease; Aerobic exercise; Peptide; Insulin resistance. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001100607 |
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| Sugayama,S.M.M.; Arslanian,C.; Sales,M.M.; Carneiro-Sampaio,M.. |
| Rubinstein-Taybi syndrome (RTS) is a rare developmental disorder characterized by craniofacial dysmorphisms, broad thumbs and toes, mental and growth deficiency, and recurrent respiratory infections. RTS has been associated with CREBBP gene mutations, but EP300 gene mutations have recently been reported in 6 individuals. In the present study, the humoral immune response in 16 RTS patients with recurrent respiratory infections of possible bacterial etiology was evaluated. No significant differences between patients and 16 healthy controls were detected to explain the high susceptibility to respiratory infections: normal or elevated serum immunoglobulin levels, normal salivary IgA levels, and a good antibody response to both polysaccharide and protein... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rubinstein-Taybi syndrome; High IgM levels; B lymphocyte; Antibody response. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001200011 |
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